Metabolic adaptation in obesity and type II diabetes: myokines, adipokines and hepatokines

KJ Oh, DS Lee, WK Kim, BS Han, SC Lee… - International journal of …, 2016 - mdpi.com
Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these
conditions. Whole-body insulin resistance and its improvement are the result of the
combined actions of each insulin-sensitive organ. Among the fundamental molecular
mechanisms by which each organ is able to communicate and engage in cross-talk are
cytokines or peptides which stem from secretory organs. Recently, it was reported that …

Metabolic Adaptation in obesity and type II diabetes: myokines, adipokines and hepatokines.

OKJ Oh KyoungJin, LDS Lee DaSom… - 2017 - cabidigitallibrary.org
Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these
conditions. Whole-body insulin resistance and its improvement are the result of the
combined actions of each insulin-sensitive organ. Among the fundamental molecular
mechanisms by which each organ is able to communicate and engage in cross-talk are
cytokines or peptides which stem from secretory organs. Recently, it was reported that …
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